How to Design Antibodies (with AI) @btnaughton is one of the best applied practitioners in the rapidly evolving world of computational protein design. Today, he published a step-by-step primer on the five steps that go into this new science: 1. Choosing a Target 2. Preparing the Target Structure 3. Running a Design Campaign 4. Filtering and Selecting Candidates 5. Experimentally Validating the Results Worth reading to better understand this frontier. It's also a great resource for understanding how the different models and products in this space can be compared right now.